I definitely feel like it should not have taken my going down a rabbithole about historical ammunition explosion incidents to learn about this one,

the destruction of a Florida fort in 1816 by the US government, resulting in 334 casualties, mostly escaped enslaved people and Native families there

Screenshot from the Wikipedia article about the Battle of Negro Fort. It reads: This is the only time in its history in which the United States destroyed a community of escaped formerly enslaved Black Americans in another country. However, the area continued to attract escaped Africans until the U.S. construction of Fort Gadsden in 1818.
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