Dominant negative ADA2 mutations cause ADA2 deficiency in heterozygous carriers @jem.org rupress.org/jem/article/... preview by @bogunoviclab.bsky.social rupress.org/jem/article/... @isabellemeyts.bsky.social
Waggoner Lab
@labwaggoner.bsky.social
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Focused on innate immune mechanisms governing pathogenesis of disease and on NK-cell based therapies for disease. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer.
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Obesity-associated saturated long-chain fatty acids regulate lung macrophage phenotype and function at steady state and during lung inflammation www.science.org/doi/10.1126/...
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An engineered Dsg3-Fc fusion protein delays disease onset and reduces severity in pemphigus vulgaris without inducing global immunosuppression www.science.org/doi/10.1126/...
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Vascular remodeling and maturation in arteriovenous fistulas are improved by mesenchymal stem cells www.science.org/doi/10.1126/...
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T cells produce IL-17 in RDEB-associated severe inflammatory dermatosis www.science.org/doi/10.1126/...
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Targeting acid ceramidase enhances collagen degradation by hepatic stellate cells via PKCα and MMP-1, uncovering a pathway to reverse liver fibrosis www.science.org/doi/10.1126/...
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Follicular regulatory T cells promote B cell–mediated experimental neuroinflammation and are associated with multiple sclerosis activity www.science.org/doi/10.1126/...
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Synthetic carbohydrate receptors prevent viral infections by binding to conserved enveloped virus glycans on viral surfaces
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BioFuse offers a flexible approach to precisely timing gene expression and metabolic activities www.science.org/doi/10.1126/...
